We are proud to present you the first edition of our SYNENERGENE Newsletters. These Newsletters will provide you with information about a wide range of activities undertaken in this four-years project. The project's approach to the concept of Responsible Research & Innovation, its aims and activities is elucidated by project leader Christopher Coenen in the first article. An nice example of SYNENERGENE's activities is the project's cooperation with the international Genetic Engineering Machine Competition (iGEM), where students are engaged in developing scenarios. In this edition you will also find articles on the Bio-Fiction Science Art Film Festival 2014 as an example of what a cultural dimension could add to the discourse on synthetic biology, the artemisinin case that highlights the risk of promises that can backfire, and the model of “trading-zones” that has been developed to discuss and explore possibilities for translating knowledge and uncertainty into responsible decision making and governance processes.

This edition can be viewed online at http://www.lisconsult.nl/index.php?option=com_acymailing&ctrl=archive&ta...